Lastly, clonidine improves neuraxial opioids and, in combination with fentanyl, interacts within an additive fashion, which often can decrease the dose of each component by sixty% for postoperative analgesia. For those who get dizzy when standing: This affliction known as orthostatic hypotension. Clonidine will make this affliction even worse. https://www.proleviate.com/post/the-new-pain-killer-conolidine