Mavacamten will reduce the level or influence of ethinylestradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Progestin and ethinyl estradiol are CYP3A4 substrates. Mavacamten could lessen systemic exposures of ethinyl estradiol and progestin, which can produce contraceptive failure or an increase in breakthrough bleeding. fedratinib will https://lisaw949frd8.eveowiki.com/user