Our latest scientific studies suggest that this is because of faulty trafficking of late endosomes to lysosomes, with concomitant homotypic fusion from the impacted vesicular compartments [five]. The defect in lysosome-directed trafficking also has an effect on autophagic flux, with resultant accumulation of autophagosomes [5]. In the long run, the https://paulg208aej1.wikiannouncing.com/user